_________（49）A.In spite of this handicap however

_________（49）

A.In spite of this handicap,however,he continued to write music

B.Because of irregular payments from his publishers and erratic support from his patrons,he was troubled by financial worries throughout his adult life

C.His life was marked by a passionate dedication to independence

D.When his mother died,Beethoven,then a young man,was named guardian of his two younger brothers

E.Although Beethoven’s personality may have been untamed,his music shows great discipline and control,and this is how we remember him best

F. Today his music is still being played all over the world